1. Full name:Chu Thanh Binh                                                                  2. Sex: Female

3. Date of birth: 1st Nov. 1974                                                               4. Place of birth: Hanoi

5. Admission decision number: No 3972/QD-DHKHTN, dated on 24th Nov, 2016 by Rector of VNU University of Science.

6. Changes in academic process:

7. Official thesis title: Studied nematophagous fungus in Piper nigrum L. Pepper which are produced nematode killing preparations.

8. Major: Microbiology                                                                           9. Code: 9420101.07

10. Supervisors:            1. Assoc.Prof.Dr. Bui Thi Viet Ha

                                    2. Dr. Ho Tuyen

11. Summary of the new findings of the thesis:

- Selected one indigenous strain of fungi from pepper soil in Dak Lak province with the highest capable killing nematode; Bioproduct were tested on a 3 ha scale/model yielded a 20% yield increase for grade 0 garden.

- Developed a new gene transfer process using Agrobacterium tumefaciens based on uridine/uracil auxotrophic mechanism. Transformants efficiency was 10 times higher than the previous research. The transfomant PE858 was screened from a library of transgenic with 7 times more capable killing nematode activity than the natural strain.

12. Practical applicability, if any:

- Test on probiotics P1 to kill nematode Meloidogyne sp. on 3 ha model pepper garden in Eaba commune, Buon Don district, Dak Lak province.

- Testing of probiotics P1 to kill nematode Meloidogyne sp. at Pepper gardens in the area of Dak Nong and Gia Lai provinces.

13. Further research directions, if any:

- Research on genetic modification of Paecilomyces lilacinus P1 strain to investigate the function of some genes related to nematophagous killing mechanism.

- Deploying additional application testing models in some areas of Tay Nguyen, collecting additional data for the process of testing liquid probiotics for integrative management of nematode and fungal diseases of pepper roots for sustainable development in Tay Nguyen.

14. Thesis-related publications:

            1. Chu Thanh Binh, Bui Thi Viet Ha, Ho Tuyen, Nguyen Phuong Nhue (2017), “Biological characteristics of the Paecilomyces variotii NV01 strain isolated in Dak Lak Pepper soil” Natural Sciences and Technology, VNU 33 (1S), 42-48.

            2. Chu Thanh Binh, Nguyen Phuong Nhue, Ho Tuyen, Bui Thi Viet Ha (2019), “Purification and characterization of chitinase from the Nematode – Fungus Paecilomyces sp. P1”. Natural Sciences and Technology, VNU 35 (1), 90-96.

            3. Chu Thanh Binh, Tran Van Tuan, Bui Thi Viet Ha (2019), “Optimization of medium composition for enhancing chitinase production of Paecilomyces sp. P1   strain by using response surface methodology”, Tạp chí Công nghệ sinh học 17 (2), 301-308.            

            4. Chu Thanh Binh, Tran Van Tuan, Tran Bao Tram, Bui Thi Viet Ha (2019), “Determination of protease and chitinase activities from Paecilomyces variotii NV01 isolated from Dak Lak pepper soil”, Vietnam Journal of Science, Technology and Engineering 61 (4), 33-38.

            5. Chu Thanh Binh, Bui Thi Viet Ha, Van-Tuan Tran (2019), A new and highly efficient Agrobacterium-mediated transformation system based on the uridine/uracil auxotrophic mutant in the nematophagous fungus Paecilomyces lilacinus P1. Manuscript submitted.

            6. Chu Thanh Binh, Tran Van Tuan, Bui Thi Viet Ha (2020), Testing of bio-product P1 to control nematodes causing disease on black pepper in Dak Lak province, Journal of Vietnam Agricultural Science and Technology 4 (113), 126-131.