Phytochemical investigation of the roots of Stemona cochinchinensis led to the isolation and structure elucidation of a new pyrido[1,2-a]azepine-type alkaloid, stemocochinamine (1), and of four new pyrrolo[1,2-a]azepine-type alkaloids, bisdehydrostemocochinine (2), isobisdehydrostemocochinine (3), neostemocochinine (4), and isoneostemocochinine (5), together with six known alkaloids. Their structures were established on the basis of extensive 1D- and 2D-NMR analyses in combination with HR-MS experiments. © 2007 Verlag Helvetica Chimica Acta AG.

Lin L.-G., Dien P.-H., Tang C.-P., Ke C.-Q., Yang X.-Z., Ye Y.

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Từ khóa : Alkaloids; Stemona cochinchinensis; Mass spectrometry; Molecular structure; Nuclear magnetic resonance spectroscopy; Amines; alkaloid; bisdehydrostemocochinamine; isobisdehydrostemocochinamine; isoneostemocochinamine; neostemocochinamine; stemocochinamine; unclassified drug; article; carbon nuclear magnetic resonance; drug isolation; drug structure; mass spectrometry; medicinal plant; phytochemistry; plant root; priority journal; proton nuclear magnetic resonance; Stemona conchinchinensis; structure analysis