Four new natural neolignans and lignans, which were given the trivial names odoratisols A-D (1-4), together with (-)-licarin A, kachirachirol B, obovatifol, and machilin-I were isolated from the air-dried bark of the Vietnamese medicinal plant Machilius odoratissima NEES (Lauraceae). Their absolute structures were determined on the basis of spectroscopic analyses including circular dichroism spectra. © 2006 Pharmaceutical Society of Japan.

Phan M.G., Phan T.S., Matsunami K., Otsuka H.

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Từ khóa : austrobailignan 7; futokadsurin b; kachirachirol b; licarin a; lignan derivative; machilin i; neolignan; obovatifol; odoratisol; plant extract; unclassified drug; verrucosin; angiosperm; article; circular dichroism; drug design; drug structure; drug synthesis; Machilus odoratissima; medicinal plant; proton nuclear magnetic resonance; spectroscopy; Chromatography, Thin Layer; Circular Dichroism; Lauraceae; Lignans; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Bark; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Vietnam