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Information on Doctoral thesis of Fellows Luu Manh Quynh

1. Full name: Luu Manh Quynh                                       2. Sex: Male

3. Date of birth: Dec, 10th 1980                                     4. Place of birth: Hai Phong

5. Admission decision number: No 3641/QĐ-SĐH dated on 26/10/2011 by Rector of VNU University of Science.

6. Changes in academic process:

Extended time by decision No 1032/QĐ-ĐHKHTN dated on 25/04/2017 and No 595/QD-ĐHKHTN date on 06/03/2018 by Rector of VNU University of Science.

7. Official thesis title: “Synthesis of PbS semiconductor nanomaterial, Au, Ag noble-metal nanomaterials and their applications in biosensor fabrication”

8. Major: Solid State Physics                                                     9. Code: 9440130.02

10. Supervisors:

                                    1st Supervisor: Assoc. Prof. Dr. Le Van Vu

                                    2nd Supervisor: Assoc. Prof. Dr. Nguyen Ngoc Long.   

11. Summary of the new findings of the thesis

- Successfully fabricated a glucose oxidase (GOx)-based enzymatic glucose sensor using PbS nanoparticles synthesized via laser annealing-modified sonochemical method. Maximum sensitivity of the sensor was 546,2 µAcm-2mM-1.

- The direct interaction between the PbS nanoparticles and SH-containing organic materials was estimated by ab initio calculation, which consequently lead to the charge-transfer between the nanoparticles and organic molecules and gave explanation to the sensitivity enhancement of the PbS-based enzymatic glucose sensor.

- Successfully fabricated a stem-cell counting system, in which the blood stem cells concentration from bone-marrow was determined by total impedance method after being collected by Fe3O4-Ag – activated magnetic separation.

- The conjugation efficiency between the Fe3O4-Ag nanoparticles and the anti-CD34 antibody was firstly estimated by using the magnetic property of the particles and fluorescence of the ECD dye that linked with the antibody.

12. Practical applicability, if any:

13. Further research directions, if any

14. Thesis-related publications:

[1] Luu Manh Quynh, Chu Tien Dung, Bach Thi Mai, Hoang Van Huy, Nguyen Quang Loc, Nguyen Quang Hoa, Pham Tuan Thach, Bui Viet Anh, Chu Thi Thao, Nguyen Hoang Nam, Hoang Thi My Nhung, Nguyen Ngoc Long, Le Van Vu (2018), “Development of Fe3O4/Ag core/shell-based multifunctional immunomagnetic nanoparticles for isolation and detection of CD34+ stem cells” Journal of Immunoassay and Immunochemistry 39(3), pp. 308-322.

[2] Cong Doanh Sai, Manh Quynh Luu, Van Vu Le, Phuong Mai Nguyen, Nguyen Hai Pham, Viet Tuyen Nguyen, Xuan Quy Nguyen, Quoc Khoa Doan, Thi Ha Tran (2017), “Fast Synthesis of PbS Nanoparticles for Fabrication of Glucose Sensor with Enhanced Sensitivity”, Journal of Electronic Materials 46(6), pp. 3674-3680

[3] Nguyen Thuy Trang, Luu Manh Quynh, Tran Van Nam, Hoang Nam Nhat (2013), “Charge transfer at organic-inorganic interface of surface-activated PbS by DFT method”, Surface Science 608, pp 67-73.

[4] Luu Manh Quynh, Nguyen Hoang Nam, K. Kong, Nguyen Thi Nhung, I. Notingher, M. Henini, Nguyen Hoang Luong (2016), “Surface-Enhanced Raman Spectroscopy Study of 4-ATP on Gold Nanoparticles for Basal Cell Carcinoma Fingerprint Detection”, Journal of Electronic Materials 45(5), pp. 2563-2568.

[5] Luu Manh Quynh, Nguyen Minh Hieu, Nguyen Hoang Nam (2014), “Fast DNA diagnostic using Fe3O4 magnetic nanoparticles and light emitting ZnS/Mn nanoparticles”, VNU Journal of Science: Mathematics – Physics 30(3), pp. 1-11.

[6] Sai Cong Doanh, Luu Manh Quynh (2015) “Highly sensitive enzyme based glucose sensor using lead sulfide nanocrystals”, VNU Journal of Science: Mathematics – Physics 31(2), pp. 61-67.

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