The possible use of an electrode modified with electroactive conductive poly(3-methylthiophene) (PMeT)/Nafion as a chemical sensor was investigated for the voltammetric analysis of Dopamine (DA). The electrochemical behavior of dopamine was examined by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. By using a PMeT-modified glassy carbon (GC/PMeT) electrode, DA and Ascorbic Acid (AA) signals could be separated but the AA at high concentrations still caused significant interference by overlapping the DA peak. In comparison to the GC/PMeT electrode, the glassy carbon (GC/Nafion/PMeT) electrode modified with hybrid film Nafion/PMeT was found to permit a superior separation by shifting the oxidation of AA peak toward the less positive potential. The DPV curves for a mixture of DA and AA at an GC/Nafion/PMeT electrode in a 0.1 M H₂SO₄ solution showed peaks of DA and AA, at 0.45 and 0.21 V, respectively, indicating that the difference in the oxidation potential was 240 mV. In the 0.1 M H₂SO₄ solution, the oxidation peak current on the differential pulse voltammograms for the GC/PMeT electrode increased linearly with the concentration of DA in the range 1 × 10^-6 to 1 × 10^-3 M, and the oxidation peak current on the differential pulse voltammograms for the GC/Nafion/PMeT electrode in the range 5 × 10^-7 to 2 × 10^-4 M. The DA detection sensitivity of the GC/Nafion/PMeT electrode (26.7 μA μM^-1 cm^-2) was 22 times higher than that of the GC/PMeT electrode (1.21 μA μM^-1 cm^-2). © 2009 Springer Science+Business Media B.V.

Huong V.T., Shimanouchi T., Quan D.P., Umakoshi H., Viet P.H., Kuboi R.

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Từ khóa : Ascorbic acids; Concentration of; Detection sensitivity; Differential pulse voltammetry; Differential pulse voltammograms; Electroactive; Electrochemical behaviors; High concentration; Hybrid film; Modified glassy carbon electrode; Oxidation peak; Oxidation potentials; Poly(3-methylthiophene) (pMeT); Positive potential; Selective detection; Voltammetric analysis; Bioelectric phenomena; Brain; Cyclic voltammetry; Glass membrane electrodes; Ketones; Organic acids; Oxidation; Glassy carbon